Also in this section

• Studies
• Managing Return-to-play Decisions Following Mild Traumatic Brain Injury - mTBI
• Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation - NICE-SUGAR
• Retrospective Analysis of Trauma Transfers - RATTS
• Saline vs. Albumin Fluid Evaluation Study - SAFE
• Saline vs. Albumin Fluid Evaluation Translation of Research Into Practice Study - SAFE TRIPS

Saline vs. Albumin Fluid Evaluation Translation of Research Into Practice Study - SAFE TRIPS

This is an international cross sectional observational study to examine fluid resuscitation practice in intensive care unit (ICU) patients across 24 countries.

Aims

The study seeks to:

• document current practice in fluid resuscitation
• determine if there are identifiable patient characteristics associated with choice of fluid
• determine whether there are identifiable national or regional variations in the choice of resuscitation fluid (not explained by patient characteristics), and
• establish an international collaboration that will conduct future fluid resuscitation trials, and provide a benchmark against which individual hospitals and ICUs can compare their practices.

Method

Data on all resuscitation fluids administered to patients in the study ICUs on a pre-determined study day(s) was collected. Eligible patients were all patients who were in the ICU during the study day, this includes all the patients who were present at the start of the study day and every patient admitted to the unit during the study day.

Study Status

Over 390 centers from 24 countries registered participated on one of the three nominated data collection days. Data for 5339 patients have been entered into the study database and final data checks are being completed.

Institute Investigators

• Simon Finfer
• John Myburgh
• Robyn Norton
• Colman Taylor

Major Collaborators

Australia

• The ANZIC Research Centre

Brazil

• Dr Otavio Berwanger- Moinhos de Vento Hospital, Porto Alegre

China

• Professor An - Peking University Health Science Centre
• Dr Du Bin - Peking Union Hospitals

Canada

• Professor Paul Hebert, Dr Lauralyn McIntyre, Dr Alan Tinmouth - University of Ottawa
• Professor Deborah Cook, McMaster University Health Center, Hamilton, Ontario

United Kingdom

• Dr. Brian Cuthbertson, Aberdeen
• Dr J Duncan Young, Oxford and UK Intensive Care Society
• Dr. Timothy Walsh, Edinburgh
• Dr Danny McAuley, Belfast

France

• Professor Laurent Brochard, Dr Frederique Schortgen - Paris

Germany

• Dr Frank Brunkhorst and Professor Konrad Reinhardt - Jena (German Sepsis Network)

Ireland

• Dr Brian Marsh - Dublin

Italy

• GIViTi (Gruppo Italiano per la Valutazione degli Interventi in Terapia Intensiva)

Japan

• Dr Hiroshi Morimatsu, Okayama

New Zealand

• Dr Colin McArthur, Auckland

Scandinavian Critical Care Trials Group

• Dr Anders Perner, Copenhagen, Denmark
• Dr Anders Aneman, Gothenburg, Sweden
• Dr Anne Berit Guttormsen, Bergen, Norway
• Dr Sigurbergur Karason, Reykjavik, Iceland
• Dr Jyrki Tenhunen, Tampere,Finland

Switzerland

• Dr Tobias Merz, Professor Jukka Takala - Bern

USA

• Dr Nicholas Vlahakis, Mayo Clinic, Rochester
• Dr Thompson Taylor and Dr. Aaron Waxman - Massachusetts General Hospital, Boston
• Dr John Kellum and Dr. Raghavan Murugan, University of Pittsburgh School of Medicine
• Dr Stephen Cohn - The University of Texas Health Science Centre, San Antonio
• US Army Institute of Surgical Research

Funders

• The George Institute